| Sasmili | One who is always smiling. |
| Sativa | A name meaning pure and active. |
| Satlim | A person of pure, truthful heart. |
| Saudia | One who brings luck and fortune. |
| Sauna | A place of warmth and relaxation. |
| Savady | A person who is very intelligent. |
| Savah | A name meaning peaceful or calm. |
| Saveeta | One who is bright and radiant. |
| Sayeedha | A noble and blessed lady. |
| Sayjol | River Water, Flowing Calm Water |
| Sayumi | A small, beautiful flower. |
| Sayyeda | A noble and honored lady. |
| Sazila | A calm and peaceful soul. |
| Sbahat | A name meaning beauty and grace. |
| Scolace | To offer solace and consolation. |
| Sealtiel | my desire is God |
| Seattle | Derived from the Lushootseed word 'si'ahl', meaning 'by the water' |
| Sedehanna | One who is simple and honest. |
| Seemran | A name meaning remembrance. |
| Seerthi | A person of great renown or fame. |
| Sehab | Refers to a shooting star or light. |
| Sehjot | The divine light of inner peace. |
| Selestia | A name meaning heavenly one. |
| Selestyne | Derived from the Latin word for heaven. |
| Seloua | An Arabic name meaning comfort or solace. |
| Selvakala | Tamil name meaning art of prosperity. |
| Selvazhaki | A woman who is beautiful and rich. |
| Semara | One who is cherished and beloved. |
| Sembathi | A woman of noble and high status. |
| Semeera | One who is Fulfilled |
| Semika | One who brings great joy. |
| Semla | A name meaning sweet delight. |
| Semona | A variant of Simone meaning heard. |
| Seniya | Worthy of praise and admiration |
| Senumitha | A friend who brings happiness. |
| Seosamhin | The Lord Increases |
| Sep | A name meaning to be distinct. |
| Serin | Fortunate Discovery |
| Serita | a form of Sarita |
| Setareh | A Persian name meaning the bright star. |