| Drexel | Drexel is a surname of German origin, derived from 'Drechsel,' meaning 'turner' or 'woodworker'. |
| Drika | Ruler of the house |
| Druin | Druin is a variant of the name Druid, meaning a wise and knowledgeable spiritual leader or priest. |
| Du | A name meaning head or chief. |
| Du Toit | From the thorn tree, a surname likely derived from a geographical location in South Africa. |
| Duangkamol | A name meaning heart or soul. |
| Duanne | A name meaning dark or black. |
| Duanphen | A name meaning full moon. |
| Dublin | From the Gaelic 'Dubh Linn', meaning 'black pool' or 'dark pool', referring to a dark tidal pool. |
| Dulci | A name meaning sweet or kind. |
| Dulcibella | A name meaning sweet beauty. |
| Dumbledore | Bumblebee, a type of insect, likely derived from the Old English 'dumbel' meaning 'to hum' or 'to buzz'. |
| Dumer | Dumer is a surname of French origin, possibly derived from the Old French word 'dumier,' meaning 'to murmur' or 'to whisper'. |
| Dumisani | Gift of God, a name of African origin, commonly used in South Africa and other parts of Africa. |
| Durwood | Durwood is a surname of English origin, derived from 'dour' meaning strong and 'wood' meaning forest or woods. |
| Dusit | Fourth land of heaven |
| Dutton | Dutton is an English surname derived from the Old English words 'dun' meaning hill and 'tun' meaning settlement. |
| Dwynwen | Fair conduct (an early saint) |
| Dylanne | Born from the deep ocean. |
| Dyone | A divine or heavenly being. |
| Dzhokhar | Dzhokhar is a Turkic name meaning 'bright' or 'shining', derived from the word 'jokh' meaning 'light'. |
| Dzigar | Dzigar is a Tibetan Buddhist title meaning 'precious jewel' or 'treasured one', often used for a lama. |
| Eadburg | Wealthy fortress |
| Eadburga | Wealthy fortress |
| Eade | Wealthy protector of lands. |
| Eadu | A name meaning rich or happy. |
| Eald | An old and wise individual. |
| Ealish | A noble and kind person. |
| Eamhair | A Gaelic name meaning swift. |
| Eann | God is gracious; in the bible; one of the apostles |
| Eanne | God is gracious |
| Earnestine | Battle; seriousbusiness |
| Easten | From the east, or sunrise. |
| Eastman | Eastman is a surname of English origin, derived from 'east' and 'man,' meaning 'man from the east'. |
| Eastun | A town located in the east. |
| Eastyn | One who comes from the east. |
| Eathan | Strength; firmness; long-lived |
| Ebb | The tide of the sea, a decrease or decline, often used to describe a gradual or steady reduction. |
| Ebbony | A deep, dark, black wood. |
| Ebele | Mercy or kindness from God. |