| DIARA | Name of French-speaking West Africa, meaning "gift." |
| Diata | A name meaning a noble person. |
| DIJI | Ibo of Nigeria name meaning "farmer." |
| Dinari | A name meaning related to the sun. |
| DOBI | Kiswahili word meaning "a person who does laundry." |
| DOLIE | A popular Somali name, meaning unknown. |
| Dost | A name meaning a loyal friend. |
| Drama | A play or theatrical work. |
| Duka | A name meaning a small village. |
| Dulani | Malawian name meaning 'cutting'. |
| Dumaka | Nigerian name meaning 'help out'. |
| Dume | A name meaning silent strength. |
| Dumi | A name meaning small and sweet. |
| DZIGBODE | Ewe of Ghana name meaning "patience." |
| Ebere | Mercy or grace from the Lord |
| EBIERE | Ijaw of Niger female name. Meaning unknown. |
| EDET | Ibibio and Efik of Nigeria name meaning "born on market day." |
| EFFIOM | Efik of Nigeria male name meaning "crocodile." |
| EFFIWAT | Nigerian female name of unknown origin. |
| EFIA | Fante of Ghana name for females born on Friday. |
| EFRA | A popular female name in Egypt. |
| Efuru | Daughter of heaven |
| Ehioze | Nigerian name meaning 'not jealous'. |
| Ehisuonria | the holy spirit leads man |
| Ekon | The one who is truly singular. |
| Elewa | One who is very intelligent. |
| ELIMU | A Kiswahili word meaning "science, knowledge." |
| Ellema | A name of uncertain origin and meaning. |
| Ellone | A name meaning light or shining. |
| Elom | A name meaning God is with me. |
| Elon | A name meaning oak tree or strong. |
| Elroi | Variant of Elroy: The king. |
| Emene | A name meaning to be complete. |
| ERASTO | An East African name meaning "man of peace." |
| Erik | A name meaning eternal ruler. |
| ESHE | Swahili female name meaning "life." |
| ESI | Ewe and Fante of Ghana name meaning "born on Sunday." |
| ESIANKIKI | A Masai and Tanzania word meaning "young maiden." |
| ESINAM | Ewe of Ghana name meaning "God heard me." |
| ESSIEN | Ochi and Ga of Ghana name meaning "sixth born." Also, Ibibio and Efik of Nigeria name meaning "belongs to everyone." |