| Sephali | A fragrant, blooming flower. |
| Sephare | A name meaning beautiful bird. |
| Sephiroth | Hebrew name meaning 'number' or 'count' |
| Sequoyah | Derived from a giant redwood tree. |
| Serafiina | Form of Seraphina |
| Seraide | A name meaning a bright star. |
| Seraina | Clear, Bright, Variant of Serene |
| Serana | Meaning a calm and serene soul. |
| Sere | Meaning dry or withered earth. |
| Serenella | Clear, Bright, Variant of Serene |
| Sergia | Derived from a Roman family name. |
| Serhilde | Armed Warrior Woman |
| Serica | Meaning silk or silklike fabric. |
| Serin | Fortunate Discovery |
| Serita | a form of Sarita |
| Serjio | Meaning a faithful attendant. |
| Serlin | A name meaning clear and bright. |
| Serlina | Meaning a peaceful, gentle girl. |
| Sermin | One who is serene and calm. |
| Serra | Burning One, Princess |
| Serrana | A woman from the mountains. |
| Serri Rafael | Italian name meaning 'rocky' and 'God is healer' |
| Serrilda | Armed Warrior Woman |
| Serry Rafael | Variant of Serri, meaning 'rocky' and 'God is healer' |
| Servana | One who serves with devotion. |
| Servause | A name meaning to be helpful. |
| Servia | Daughter of those who Serve |
| Servio | To protect or keep safe now. |
| Serviya | A dedicated, loyal servant. |
| Seryozha | Russian name meaning 'serious' or 'sincere' |
| Sesame | Resembling the Flavorful Seed |
| Seshamma | Goddess of the serpent king. |
| Seshini | One who is wise and radiant. |
| Sesiilia | A blind but musical person. |
| Sesiilja | A name meaning heavenly song. |
| Sesilja | A variant of Cecilia meaning blind. |
| Sessaley | A name meaning from the dry meadow. |
| Sesseelya | A melodic form of the name Cecilia. |
| Sessi | A short form meaning blind or dim. |
| Sessile | Meaning attached directly at base. |