| Semuel | God has heard the prayer. |
| Senaculus | From the Latin for 'old' or 'wise' |
| Senehauz | Old house or old home |
| Senemagli | Old magician or wise sorcerer |
| Senemaglos | Old wise or old magician |
| Sennianus | From the Latin for 'old' or 'wise' |
| Senomagli | Old magician or wise sorcerer |
| Senomaglos | Old wise or old magician |
| Senorix | An ancient king of the land. |
| Sentraille | From the Old French for 'castle' or 'fortress' |
| Sentwine | From the Old French for 'new wine' |
| Seofeca | From the Old English for 'divine' or 'holy' |
| Servanus | From the Latin for 'servant' or 'slave' |
| Sessa | From the Latin for 'seat' or 'throne' |
| Setibogius | From the Latin for 'seven gods' |
| Seuuard | Guardian or protector |
| Seuuardus | From the Latin for 'guardian' or 'protector' |
| Sewal | Sea; Victorious Rule over the Sea |
| Shaexon | From the Old English for 'son of the king' |
| Shahm | From the Arabic for 'king' or 'ruler' |
| Sharn | A person from the open plain. |
| Shaunte | Derived from the Old English 'scēoht,' meaning 'bright' or 'shining.' |
| Shavin | One who is bright and radiant. |
| Sheard | From the Old English 'scēard,' meaning 'bright' or 'shining.' |
| Shef | Possibly derived from the Old English 'scēoht,' meaning 'bright' or 'shining.' |
| Sheffy | A peaceful meadow dweller. |
| Shelten | From the Old English 'scelten,' meaning 'bright' or 'shining.' |
| Sherik | One who has Already Left |
| Sherly | A bright meadow or clearing. |
| Shermie | One who dwells in a meadow. |
| Sherwan | A brave lion of the forest. |
| Shiko | Possibly derived from the Old English 'scīc,' meaning 'bright' or 'shining.' |
| Shingo | Victorious; Humility |
| Shirman | A man from the bright shire. |
| Sibert | Derived from the Old English 'sibb,' meaning 'friend' or 'ally.' |
| Sibill | From the Old English 'sibb,' meaning 'friend' or 'ally.' |
| Sibwine | From the Old English 'sibb,' meaning 'friend' or 'ally,' and 'wine,' meaning 'friend' or 'ally.' |
| Sicel | A person from Sicily, Italy. |
| Sicela | Victory of the people |
| Sideman | Man by the side |